PsyMRI is aimed at a multicenter-based utilization of already existing resting-state magnetic resonance data with a focus on major depressive disorder (MDD) and neurodegenerative diseases.
By sharing datasets between collaborating sites, problems concerning the acquisistion of suitable subjects can be overcome. Compared to healthy controls the measurement of patients via magnetic resonance imaging is complicated due to inclusion criteria. Moreover the number of patients in some uncommon psychiatric or neurodegenerative diseases is substantially limited in general.
Exchanging datasets that have been collected in different scanning sites allows for a higher sample size to be included in studies. Furthermore statistical validations of hypotheses and group effects as well as replications of results and meta-analyses can be carried out on larger datasets.
Aggregating existing datasets is therefore thought to advance sctientific knowledge and promote progress concerning diagnosis and treatment of psychiatric and neurodegenerative diseases like depression and dementia.
Membership is achieved by signing the agreement for the multicenter use of existing imaging data and compliance with the minimum requirements specified therein. Rules concerning authorship in publications based on the consortial dataset are also included in this agreement. Local datasets can only be included if they have been acquired with approval from the local ethics comittee and included subjects gave written informed consent.
Ownership of the data remains with the providing member of the Consortium. PsyMRI is not a free data sharing initiative as included datasets are only accessible for members of the Consortium.
The submission of rs-MRI data and accompanying metadata is managed via the web-based data storage system XNAT (Extensible Neuroimaging Archive Toolkit ) where compressed DICOM raw data and spreadsheet documents can be uploaded. Datasets are then stored on a physically separated server. For integration into the XNAT structure, datasets will be validated and subjected to an anonymization process (defacing). Optionally preprocessing procedures of the MRI data can be centralized and automated. Access to the files in the XNAT structure is then only granted to full members of the Consortium.
Research Fellow
School of Psychology and Speech Pathology
Kent Street Bentley WA 6102
Curtin University, Perth
Australia
Neuroimaging in Psychiatry
Department of Psychiatry
Academic Medical Center
Meibergdreef 5
1105 AZ Amsterdam
The Netherlands
Klinik für Psychiatrie und Psychotherapie
Charité Universitätsmedizin Berlin, Campus Mitte
Charitéplatz 1
10117 Berlin
Germany
Klinik für Psychiatrie und Psychotherapie
Head of Department
Leipzigerstr. 44
39120 Magdeburg
Germany
Max Planck Institute of Psychiatry
Neuroimaging Core Unit
Kraepelinstr. 2-10
80804 Munich
Germany
Melbourne Neuropsychiatry Centre
Department of Psychiatry
The University of Melbourne
161 Barry St. Carlton, VIC 3053
Australia
Institute of Epidemiology and Social Medicine
University of Muenster
Domagkstr. 3
48129 Münster
Germany
Translational Psychiatry
Department of Psychiatry
Albert-Schweitzer-Campus 1
48149 Münster
Germany
Charité Centrum Neurologie, Neurochirurgie und Psychiatrie
Affektive Neurowissenschaften und Emotionsmodulation
Hindenburgdamm 30
12203 Berlin
Germany
Universitätsklinik Zürich
Klinik für Psychiatrie, Psychotherapie und Psychosomatik
Lenggstrasse 31
8032 Zürich
Switzerland
Universität Heidelberg
Klinik für Allgemeine Psychiatrie
Voßstr. 2
69115 Heidelberg
Germany
Department of Psychiatry and Psychotherapy
Clinical Neuroimaging
Medical University of Vienna
Waehringer Guertel 18-20
1090 Vienna
Austria
Psychiatric Brain & Body Research Group
Department of Psychiatry and Psychotherapy
Jena University Hospital
Philosophenweg 3
07743 Jena
Germany
Department of Cognitive Psychology II
Goethe-University Frankfurt
Theodor-W.-Adorno-Platz 6
60323 Frankfurt/Main
Germany
Tianjin Anning Hospital
Tianjin City 300300
China
Clinical Affective Neuroimaging Laboratory
ZENIT-Gebäude
Haus 65
Leipziger Str. 44
39120 Magdeburg
Germany
German Center for Neurodegenerative Diseases (DZNE)
Gehlsheimer Str. 20
18147 Rostock
Germany
Department of Psychiatry and Psychotherapy
Freiburg University Medical Center
Hauptstraße 5
79104 Freiburg
Germany
Department of Psychiatry and Psychotherapy
Klinikum rechts der Isar
TU Munich
Ismaninger Straße 22
81675 München
Germany
Department of Neuroradiology
Klinikum rechts der Isar
TU Munich
Ismaninger Straße 22
81675 München
Germany
Institute for Stroke and Dementia Research
Klinikum der Universität München
Feodor-Lynen-Straße 17
81377 München
Germany
Department of Psychiatry and Behavioral Sciences
Stanford University
Stanford, California 94305
USA
David Starr Jordan Professor and Chair
Department of Psychology
Stanford University
Stanford, California 94305
USA